Immortalized Human Tooth Pulp Stem Cell Conditioned Media
A cosmetic ingredient used as antiplaque, hair conditioning, humectant in skincare, haircare, and personal-care products sold in the European Union.
What is it?
Immortalized Human Tooth Pulp Stem Cell Conditioned Media is the growth media removed from cultures of cells isolated from human tooth pulp tissue after several days of growth. The cells are immortalized by the insertion of the human papillomavirus E6 and E7 genes, and hTERT gene. The starting media is either Dulbecco's Modified Eagle Medium which may or may not contain fetal bovine serum, or a serum-free nutrient media.
What does it do?
Immortalized Human Tooth Pulp Stem Cell Conditioned Media is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Antiplaque
reduces dental plaque, used in toothpastes and mouthwashes
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Hair conditioning
improves the appearance, feel, and manageability of hair
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Humectant
draws moisture from the air or deeper skin layers to the surface, helping skin retain water
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Oral care
used in oral-hygiene products such as toothpaste, mouthwash, and dental gels
EU regulatory status
This ingredient is banned in the European Union.
Immortalized Human Tooth Pulp Stem Cell Conditioned Media is listed under Annex II of EU Cosmetics Regulation 1223/2009 (entry 416), making it prohibited in cosmetic products placed on the EU market.
Frequently asked questions
What is Immortalized Human Tooth Pulp Stem Cell Conditioned Media?
Immortalized Human Tooth Pulp Stem Cell Conditioned Media is a cosmetic ingredient catalogued in the EU CosIng database. Immortalized Human Tooth Pulp Stem Cell Conditioned Media is the growth media removed from cultures of cells isolated from human tooth pulp tissue after several days of growth. The cells are immortalized by the insertion of the human papillomavirus E6 and E7 genes, and hTERT gene. The starting media is either Dulbecco's Modified Eagle Medium which may or may not contain fetal bovine serum, or a serum-free nutrient media.
Is Immortalized Human Tooth Pulp Stem Cell Conditioned Media allowed in cosmetics in the EU?
No. Immortalized Human Tooth Pulp Stem Cell Conditioned Media is banned for use in cosmetic products in the EU under Annex II of Regulation 1223/2009.
What does Immortalized Human Tooth Pulp Stem Cell Conditioned Media do in cosmetic products?
Immortalized Human Tooth Pulp Stem Cell Conditioned Media is declared in the EU cosmetic ingredient inventory with these functions: antiplaque, hair conditioning, humectant, oral care.
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Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 23/06/2016