Rh-Polypeptide-16
A cosmetic ingredient used as skin conditioning in skincare, haircare, and personal-care products sold in the European Union.
What is it?
rh-Polypeptide-16 is a homodimeric, recombinant, non-glycosylated, peptide, produced using the human gene for Placental Growth Factor-1 containing a one base mutation by fermentation in E. coli. This oligopeptide contains 125 amino acids and is composed of: methionine, leucine, proline, alanine, valine, glutamine, tryptophan, serine, glycine, glycine, asparagine, glutamic acid, phenylalanine, arginine, tyrosine, cysteine, aspartic acid, histidine, threonine, lysine, isoleucine
What does it do?
Rh-Polypeptide-16 is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Skin conditioning
improves the appearance, feel, and condition of skin
EU regulatory status
This ingredient is banned in the European Union.
Rh-Polypeptide-16 is listed under Annex II of EU Cosmetics Regulation 1223/2009 (entry 416), making it prohibited in cosmetic products placed on the EU market.
Frequently asked questions
What is Rh-Polypeptide-16?
Rh-Polypeptide-16 is a cosmetic ingredient catalogued in the EU CosIng database. rh-Polypeptide-16 is a homodimeric, recombinant, non-glycosylated, peptide, produced using the human gene for Placental Growth Factor-1 containing a one base mutation by fermentation in E. coli. This oligopeptide contains 125 amino acids and is composed of: methionine, leucine, proline, alanine, valine, glutamine, tryptophan, serine, glycine, glycine, asparagine, glutamic acid, phenylalanine, arginine, tyrosine, cysteine, aspartic acid, histidine, threonine, lysine, isoleucine
Is Rh-Polypeptide-16 allowed in cosmetics in the EU?
No. Rh-Polypeptide-16 is banned for use in cosmetic products in the EU under Annex II of Regulation 1223/2009.
What does Rh-Polypeptide-16 do in cosmetic products?
Rh-Polypeptide-16 is declared in the EU cosmetic ingredient inventory with these functions: skin conditioning.
What is the CAS number of Rh-Polypeptide-16?
The CAS (Chemical Abstracts Service) number for Rh-Polypeptide-16 is 797794-90-2.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 15/10/2010