Rh-Polypeptide-48
A cosmetic ingredient used as not reported in skincare, haircare, and personal-care products sold in the European Union.
What is it?
rh-Polypeptide-48 is a single chain recombinant human peptide, produced by fermentation in either Chinese hamster ovary cells (CHO) or E. coli. The starting gene is directly isolated from a human cell which codes for Laminin Subunit Beta-1 used as such or adapted to the production host. It contains a maximum of 1786 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
What does it do?
Rh-Polypeptide-48 is listed in the EU cosmetic ingredient inventory with the following declared functions:
-
Not reported
function not declared in the EU CosIng database — the substance is approved for cosmetic use, but no specific role has been categorised
EU regulatory status
This ingredient is banned in the European Union.
Rh-Polypeptide-48 is listed under Annex II of EU Cosmetics Regulation 1223/2009 (entry 416), making it prohibited in cosmetic products placed on the EU market.
Frequently asked questions
What is Rh-Polypeptide-48?
Rh-Polypeptide-48 is a cosmetic ingredient catalogued in the EU CosIng database. rh-Polypeptide-48 is a single chain recombinant human peptide, produced by fermentation in either Chinese hamster ovary cells (CHO) or E. coli. The starting gene is directly isolated from a human cell which codes for Laminin Subunit Beta-1 used as such or adapted to the production host. It contains a maximum of 1786 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
Is Rh-Polypeptide-48 allowed in cosmetics in the EU?
No. Rh-Polypeptide-48 is banned for use in cosmetic products in the EU under Annex II of Regulation 1223/2009.
What does Rh-Polypeptide-48 do in cosmetic products?
Rh-Polypeptide-48 is declared in the EU cosmetic ingredient inventory with these functions: not reported.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 25/04/2019