Sh-Oligopeptide-81
A cosmetic ingredient used as not reported in skincare, haircare, and personal-care products sold in the European Union.
What is it?
sh-Oligopeptide-81 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene, which is a synthesized copy of the human gene that codes for Histatin-3, is used as such or adapted to the production host. Histatin-3 contains a maximum of 51 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids. (sh-Oligopeptide-81 is included in the INCI database as a reference for the definition of other INCI Names, and might not be a marketed cosmetic ingredient).
What does it do?
Sh-Oligopeptide-81 is listed in the EU cosmetic ingredient inventory with the following declared functions:
-
Not reported
function not declared in the EU CosIng database — the substance is approved for cosmetic use, but no specific role has been categorised
EU regulatory status
Sh-Oligopeptide-81 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Sh-Oligopeptide-81?
Sh-Oligopeptide-81 is a cosmetic ingredient catalogued in the EU CosIng database. sh-Oligopeptide-81 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene, which is a synthesized copy of the human gene that codes for Histatin-3, is used as such or adapted to the production host. Histatin-3 contains a maximum of 51 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids. (sh-Oligopeptide-81 is included in the INCI database as a reference for the definition of other INCI Names, and might not be a marketed cosmetic ingredient).
Is Sh-Oligopeptide-81 allowed in cosmetics in the EU?
Yes. Sh-Oligopeptide-81 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Sh-Oligopeptide-81 do in cosmetic products?
Sh-Oligopeptide-81 is declared in the EU cosmetic ingredient inventory with these functions: not reported.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 12/10/2020