Sh-Polypeptide-111
A cosmetic ingredient used as skin conditioning, skin protecting in skincare, haircare, and personal-care products sold in the European Union.
What is it?
sh-Polypeptide-111 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Disintegrin and Metalloproteinase Domain-containing Protein 15 used as such or adapted to the production host. It contains a maximum of 863 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
What does it do?
Sh-Polypeptide-111 is listed in the EU cosmetic ingredient inventory with the following declared functions:
-
Skin conditioning
improves the appearance, feel, and condition of skin
-
Skin protecting
helps shield skin from external environmental factors
EU regulatory status
Sh-Polypeptide-111 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Sh-Polypeptide-111?
Sh-Polypeptide-111 is a cosmetic ingredient catalogued in the EU CosIng database. sh-Polypeptide-111 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Disintegrin and Metalloproteinase Domain-containing Protein 15 used as such or adapted to the production host. It contains a maximum of 863 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
Is Sh-Polypeptide-111 allowed in cosmetics in the EU?
Yes. Sh-Polypeptide-111 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Sh-Polypeptide-111 do in cosmetic products?
Sh-Polypeptide-111 is declared in the EU cosmetic ingredient inventory with these functions: skin conditioning, skin protecting.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 17/04/2018