Sh-Polypeptide-121
A cosmetic ingredient used as film forming, skin conditioning in skincare, haircare, and personal-care products sold in the European Union.
What is it?
sh-Polypeptide-121 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Collagen alpha-1(XXI) chain used such or adapted to the production host. It contains a maximum of 957 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
What does it do?
Sh-Polypeptide-121 is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Film forming
forms a thin continuous film on skin, hair, or nails — used in long-wear makeup, sunscreens, and hairsprays
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Skin conditioning
improves the appearance, feel, and condition of skin
EU regulatory status
Sh-Polypeptide-121 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Sh-Polypeptide-121?
Sh-Polypeptide-121 is a cosmetic ingredient catalogued in the EU CosIng database. sh-Polypeptide-121 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Collagen alpha-1(XXI) chain used such or adapted to the production host. It contains a maximum of 957 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
Is Sh-Polypeptide-121 allowed in cosmetics in the EU?
Yes. Sh-Polypeptide-121 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Sh-Polypeptide-121 do in cosmetic products?
Sh-Polypeptide-121 is declared in the EU cosmetic ingredient inventory with these functions: film forming, skin conditioning.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 25/04/2019