Sh-Polypeptide-123
A cosmetic ingredient used as skin protecting in skincare, haircare, and personal-care products sold in the European Union.
What is it?
sh-Polypeptide-123 is a single chain recombinant human peptide, produced by fermentation in Pichia pastoris. The starting gene is synthesized to be similar to the human gene which codes for Collagen Alpha-1 (III) Chain used as such or adapted to the production host. It contains a maximum of 1466 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of all or part of the 20 standard amino acids.
What does it do?
Sh-Polypeptide-123 is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Skin protecting
helps shield skin from external environmental factors
EU regulatory status
Sh-Polypeptide-123 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Sh-Polypeptide-123?
Sh-Polypeptide-123 is a cosmetic ingredient catalogued in the EU CosIng database. sh-Polypeptide-123 is a single chain recombinant human peptide, produced by fermentation in Pichia pastoris. The starting gene is synthesized to be similar to the human gene which codes for Collagen Alpha-1 (III) Chain used as such or adapted to the production host. It contains a maximum of 1466 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of all or part of the 20 standard amino acids.
Is Sh-Polypeptide-123 allowed in cosmetics in the EU?
Yes. Sh-Polypeptide-123 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Sh-Polypeptide-123 do in cosmetic products?
Sh-Polypeptide-123 is declared in the EU cosmetic ingredient inventory with these functions: skin protecting.
What is the CAS number of Sh-Polypeptide-123?
The CAS (Chemical Abstracts Service) number for Sh-Polypeptide-123 is 1375784-79-4.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 18/10/2019