Sh-Polypeptide-127
A cosmetic ingredient used as skin protecting in skincare, haircare, and personal-care products sold in the European Union.
What is it?
sh-Polypeptide-127 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene which is a synthesized copy of the human gene that codes for Cellular Tumor Antigen p53 is used as such or adapted to the production host. It contains a maximum of 393 amino acids which may contain disulfide bonds and/or glycosylation.
What does it do?
Sh-Polypeptide-127 is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Skin protecting
helps shield skin from external environmental factors
EU regulatory status
Sh-Polypeptide-127 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Sh-Polypeptide-127?
Sh-Polypeptide-127 is a cosmetic ingredient catalogued in the EU CosIng database. sh-Polypeptide-127 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene which is a synthesized copy of the human gene that codes for Cellular Tumor Antigen p53 is used as such or adapted to the production host. It contains a maximum of 393 amino acids which may contain disulfide bonds and/or glycosylation.
Is Sh-Polypeptide-127 allowed in cosmetics in the EU?
Yes. Sh-Polypeptide-127 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Sh-Polypeptide-127 do in cosmetic products?
Sh-Polypeptide-127 is declared in the EU cosmetic ingredient inventory with these functions: skin protecting.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 21/04/2020