Allowed in EU

Sh-Polypeptide-6

A cosmetic ingredient used as humectant, skin conditioning in skincare, haircare, and personal-care products sold in the European Union.

What is it?

sh-Polypeptide-6 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Interleukin 10 used as such or adapted to the production host. It contains a maximum of 160 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.

What does it do?

Sh-Polypeptide-6 is listed in the EU cosmetic ingredient inventory with the following declared functions:

  • Humectant

    draws moisture from the air or deeper skin layers to the surface, helping skin retain water

  • Skin conditioning

    improves the appearance, feel, and condition of skin

EU regulatory status

Sh-Polypeptide-6 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.

Frequently asked questions

What is Sh-Polypeptide-6?

Sh-Polypeptide-6 is a cosmetic ingredient catalogued in the EU CosIng database. sh-Polypeptide-6 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Interleukin 10 used as such or adapted to the production host. It contains a maximum of 160 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.

Is Sh-Polypeptide-6 allowed in cosmetics in the EU?

Yes. Sh-Polypeptide-6 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.

What does Sh-Polypeptide-6 do in cosmetic products?

Sh-Polypeptide-6 is declared in the EU cosmetic ingredient inventory with these functions: humectant, skin conditioning.

Related ingredients

Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 12/11/2012