Allowed in EU

Sh-Polypeptide-98 Hexapeptide-40

A cosmetic ingredient used as humectant, skin conditioning in skincare, haircare, and personal-care products sold in the European Union.

What is it?

sh-Polypeptide-98 Hexapeptide-40 is a single chain fusion peptide, produced by fermentation in HeLa cells. The starting gene is synthesized by the fusion of the gene from sh-Polypeptide-98 and Decapeptide-40. The fusion peptide contains 485 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.

What does it do?

Sh-Polypeptide-98 Hexapeptide-40 is listed in the EU cosmetic ingredient inventory with the following declared functions:

  • Humectant

    draws moisture from the air or deeper skin layers to the surface, helping skin retain water

  • Skin conditioning

    improves the appearance, feel, and condition of skin

EU regulatory status

Sh-Polypeptide-98 Hexapeptide-40 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.

Frequently asked questions

What is Sh-Polypeptide-98 Hexapeptide-40?

Sh-Polypeptide-98 Hexapeptide-40 is a cosmetic ingredient catalogued in the EU CosIng database. sh-Polypeptide-98 Hexapeptide-40 is a single chain fusion peptide, produced by fermentation in HeLa cells. The starting gene is synthesized by the fusion of the gene from sh-Polypeptide-98 and Decapeptide-40. The fusion peptide contains 485 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.

Is Sh-Polypeptide-98 Hexapeptide-40 allowed in cosmetics in the EU?

Yes. Sh-Polypeptide-98 Hexapeptide-40 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.

What does Sh-Polypeptide-98 Hexapeptide-40 do in cosmetic products?

Sh-Polypeptide-98 Hexapeptide-40 is declared in the EU cosmetic ingredient inventory with these functions: humectant, skin conditioning.

Related ingredients

Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 20/02/2018