Silkworm Sh-Polypeptide-69
A cosmetic ingredient used as humectant, skin conditioning in skincare, haircare, and personal-care products sold in the European Union.
What is it?
Silkworm sh-Polypeptide-69 is a single chain recombinant human peptide, produced by silkworm after after using either a transient expression system or transgenesis (stable insertion of a copy of a human gene into its DNA). The starting gene is synthesized to be identical to the human gene which codes for Collagen Alpha-1 (III) Chain. It contains a maximum of 1466 amino acids, which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
What does it do?
Silkworm Sh-Polypeptide-69 is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Humectant
draws moisture from the air or deeper skin layers to the surface, helping skin retain water
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Skin conditioning
improves the appearance, feel, and condition of skin
EU regulatory status
Silkworm Sh-Polypeptide-69 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Silkworm Sh-Polypeptide-69?
Silkworm Sh-Polypeptide-69 is a cosmetic ingredient catalogued in the EU CosIng database. Silkworm sh-Polypeptide-69 is a single chain recombinant human peptide, produced by silkworm after after using either a transient expression system or transgenesis (stable insertion of a copy of a human gene into its DNA). The starting gene is synthesized to be identical to the human gene which codes for Collagen Alpha-1 (III) Chain. It contains a maximum of 1466 amino acids, which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
Is Silkworm Sh-Polypeptide-69 allowed in cosmetics in the EU?
Yes. Silkworm Sh-Polypeptide-69 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Silkworm Sh-Polypeptide-69 do in cosmetic products?
Silkworm Sh-Polypeptide-69 is declared in the EU cosmetic ingredient inventory with these functions: humectant, skin conditioning.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 25/04/2019