Cosmadex
Allowed in EU

Spilanthoyl Sh-Hexapeptide-46 Sp Amide

A cosmetic ingredient used as skin protecting, skin conditioning - humectant, skin conditioning - miscellaneous in skincare, haircare, and personal-care products sold in the European Union.

What is it?

Spilanthoyl sh-Hexapeptide-46 SP Amide is the product obtained by the reaction of Spilanthic Acid and sh-Hexapeptide-46 SP in which the C-terminus is an amide.

What does it do?

Spilanthoyl Sh-Hexapeptide-46 Sp Amide is listed in the EU cosmetic ingredient inventory with the following declared functions:

EU regulatory status

Spilanthoyl Sh-Hexapeptide-46 Sp Amide is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.

Frequently asked questions

What is Spilanthoyl Sh-Hexapeptide-46 Sp Amide?

Spilanthoyl Sh-Hexapeptide-46 Sp Amide is a cosmetic ingredient catalogued in the EU CosIng database. Spilanthoyl sh-Hexapeptide-46 SP Amide is the product obtained by the reaction of Spilanthic Acid and sh-Hexapeptide-46 SP in which the C-terminus is an amide.

Is Spilanthoyl Sh-Hexapeptide-46 Sp Amide allowed in cosmetics in the EU?

Yes. Spilanthoyl Sh-Hexapeptide-46 Sp Amide is allowed for use in cosmetic products in the EU under Regulation 1223/2009.

What does Spilanthoyl Sh-Hexapeptide-46 Sp Amide do in cosmetic products?

Spilanthoyl Sh-Hexapeptide-46 Sp Amide is declared in the EU cosmetic ingredient inventory with these functions: skin protecting, skin conditioning - humectant, skin conditioning - miscellaneous.

Related ingredients

Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 25/06/2026