Sr-Cow Polypeptide-5
A cosmetic ingredient used as skin conditioning - miscellaneous in skincare, haircare, and personal-care products sold in the European Union.
What is it?
sr-Cow Polypeptide-5 is a single chain recombinant protein produced by fermentation in E. coli. The starting gene is synthetically produced to be identical to a portion of the gene which codes for Insulin-Like Growth Factor 1, which is found in the cow, Bos taurus. The protein contains a maximum of 154 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.
What does it do?
Sr-Cow Polypeptide-5 is listed in the EU cosmetic ingredient inventory with the following declared functions:
-
Skin conditioning - miscellaneous
improves skin condition through mechanisms not classified under the more specific emollient or humectant subcategories
EU regulatory status
Sr-Cow Polypeptide-5 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Sr-Cow Polypeptide-5?
Sr-Cow Polypeptide-5 is a cosmetic ingredient catalogued in the EU CosIng database. sr-Cow Polypeptide-5 is a single chain recombinant protein produced by fermentation in E. coli. The starting gene is synthetically produced to be identical to a portion of the gene which codes for Insulin-Like Growth Factor 1, which is found in the cow, Bos taurus. The protein contains a maximum of 154 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.
Is Sr-Cow Polypeptide-5 allowed in cosmetics in the EU?
Yes. Sr-Cow Polypeptide-5 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Sr-Cow Polypeptide-5 do in cosmetic products?
Sr-Cow Polypeptide-5 is declared in the EU cosmetic ingredient inventory with these functions: skin conditioning - miscellaneous.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 25/06/2026