Sr-(Methionyl Sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 Sh-Oligopeptide-197)
A cosmetic ingredient used as hair conditioning, skin conditioning - miscellaneous in skincare, haircare, and personal-care products sold in the European Union.
What is it?
sr-(Methionyl sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 sh-Oligopeptide-197) is a single chain recombinant peptide produced by Chinese hamster ovary cells. The starting gene is synthesized by the fusion of the genes from sh-Polypeptide-3, Dipeptide-46, Oligopeptide-163, and sh-Oligopeptide-197 (q.v.) with the initiation code for methionine. The fusion peptide contains 75 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence from the 20 standard amino acids.
What does it do?
Sr-(Methionyl Sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 Sh-Oligopeptide-197) is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Hair conditioning
improves the appearance, feel, and manageability of hair
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Skin conditioning - miscellaneous
improves skin condition through mechanisms not classified under the more specific emollient or humectant subcategories
EU regulatory status
Sr-(Methionyl Sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 Sh-Oligopeptide-197) is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Sr-(Methionyl Sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 Sh-Oligopeptide-197)?
Sr-(Methionyl Sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 Sh-Oligopeptide-197) is a cosmetic ingredient catalogued in the EU CosIng database. sr-(Methionyl sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 sh-Oligopeptide-197) is a single chain recombinant peptide produced by Chinese hamster ovary cells. The starting gene is synthesized by the fusion of the genes from sh-Polypeptide-3, Dipeptide-46, Oligopeptide-163, and sh-Oligopeptide-197 (q.v.) with the initiation code for methionine. The fusion peptide contains 75 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence from the 20 standard amino acids.
Is Sr-(Methionyl Sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 Sh-Oligopeptide-197) allowed in cosmetics in the EU?
Yes. Sr-(Methionyl Sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 Sh-Oligopeptide-197) is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Sr-(Methionyl Sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 Sh-Oligopeptide-197) do in cosmetic products?
Sr-(Methionyl Sh-Polypeptide-3 Dipeptide-46 Oligopeptide-163 Sh-Oligopeptide-197) is declared in the EU cosmetic ingredient inventory with these functions: hair conditioning, skin conditioning - miscellaneous.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 30/04/2025