Sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Sh-Polypeptide-190 Sh-Polypeptide-191)
A cosmetic ingredient used as antioxidant, reducing in skincare, haircare, and personal-care products sold in the European Union.
What is it?
sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 sh-Polypeptide-190 sh-Polypeptide-191) is a single chain recombinant peptide produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the genes from Tripeptide-46, Hexapeptide-40, Decapeptide-27, sh-Polypeptide-190, and sh-Polypeptide-191 with the initiation code for methionine. The fusion peptide contains 353 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence from the 20 standard amino acids.
What does it do?
Sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Sh-Polypeptide-190 Sh-Polypeptide-191) is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Antioxidant
neutralises free radicals to slow oxidative damage to the formulation or skin
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Reducing
a reducing agent — donates electrons to break chemical bonds, used in perms and depilatories
EU regulatory status
Sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Sh-Polypeptide-190 Sh-Polypeptide-191) is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Sh-Polypeptide-190 Sh-Polypeptide-191)?
Sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Sh-Polypeptide-190 Sh-Polypeptide-191) is a cosmetic ingredient catalogued in the EU CosIng database. sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 sh-Polypeptide-190 sh-Polypeptide-191) is a single chain recombinant peptide produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the genes from Tripeptide-46, Hexapeptide-40, Decapeptide-27, sh-Polypeptide-190, and sh-Polypeptide-191 with the initiation code for methionine. The fusion peptide contains 353 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence from the 20 standard amino acids.
Is Sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Sh-Polypeptide-190 Sh-Polypeptide-191) allowed in cosmetics in the EU?
Yes. Sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Sh-Polypeptide-190 Sh-Polypeptide-191) is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Sh-Polypeptide-190 Sh-Polypeptide-191) do in cosmetic products?
Sr-(Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Sh-Polypeptide-190 Sh-Polypeptide-191) is declared in the EU cosmetic ingredient inventory with these functions: antioxidant, reducing.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 25/06/2026