Sr-(Octapeptide-53 Sh-Polypeptide-169)
A cosmetic ingredient used as skin protecting in skincare, haircare, and personal-care products sold in the European Union.
What is it?
sr-(Octapeptide-53 sh-Polypeptide-169) is a single chain recombinant peptide, produced by fermentation in Pichia. The starting gene is synthesized by the fusion of the gene from Octapeptide-53 and sh-Polypeptide-169. The fusion peptide contains 309 amino acids which may contain disulfide bonds and/or glycosylation and consists of the proper sequence of the 20 standard amino acids.
What does it do?
Sr-(Octapeptide-53 Sh-Polypeptide-169) is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Skin protecting
helps shield skin from external environmental factors
EU regulatory status
Sr-(Octapeptide-53 Sh-Polypeptide-169) is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Sr-(Octapeptide-53 Sh-Polypeptide-169)?
Sr-(Octapeptide-53 Sh-Polypeptide-169) is a cosmetic ingredient catalogued in the EU CosIng database. sr-(Octapeptide-53 sh-Polypeptide-169) is a single chain recombinant peptide, produced by fermentation in Pichia. The starting gene is synthesized by the fusion of the gene from Octapeptide-53 and sh-Polypeptide-169. The fusion peptide contains 309 amino acids which may contain disulfide bonds and/or glycosylation and consists of the proper sequence of the 20 standard amino acids.
Is Sr-(Octapeptide-53 Sh-Polypeptide-169) allowed in cosmetics in the EU?
Yes. Sr-(Octapeptide-53 Sh-Polypeptide-169) is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Sr-(Octapeptide-53 Sh-Polypeptide-169) do in cosmetic products?
Sr-(Octapeptide-53 Sh-Polypeptide-169) is declared in the EU cosmetic ingredient inventory with these functions: skin protecting.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 30/04/2025