Sr-(Polypeptide-169 Oligopeptide-178)

What is it?

sr-(Polypeptide-169 Oligopeptide-178) is a single chain recombinant peptide, produced by fermentation in Pichia pastoris. The starting gene is synthesized by the fusion of the gene from Polypeptide-169 and Oligopeptide-178. The fusion peptide contains 970 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.

What does it do?

Sr-(Polypeptide-169 Oligopeptide-178) is listed in the EU cosmetic ingredient inventory with the following declared functions:

• Surfactant - emulsifying

  surfactant that forms and stabilises emulsions of oil and water — without it, creams and lotions would separate

• Film forming

  forms a thin continuous film on skin, hair, or nails — used in long-wear makeup, sunscreens, and hairsprays

• Skin protecting

  helps shield skin from external environmental factors

• Viscosity controlling

  adjusts the thickness or flow of a formulation

• Slip modifier

  alters how a product spreads and feels on skin — typically making it glide more smoothly

EU regulatory status

Sr-(Polypeptide-169 Oligopeptide-178) is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.

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