Sr-(Sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40)
A cosmetic ingredient used as hair conditioning, skin protecting, skin conditioning - miscellaneous in skincare, haircare, and personal-care products sold in the European Union.
What is it?
sr-(sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40) is a single chain recombinant peptide, produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the gene from sh-Polypeptide-158, Tripeptide-46, and Hexapeptide-40. The fusion peptide contains 100 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.
What does it do?
Sr-(Sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40) is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Hair conditioning
improves the appearance, feel, and manageability of hair
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Skin protecting
helps shield skin from external environmental factors
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Skin conditioning - miscellaneous
improves skin condition through mechanisms not classified under the more specific emollient or humectant subcategories
EU regulatory status
Sr-(Sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40) is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Sr-(Sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40)?
Sr-(Sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40) is a cosmetic ingredient catalogued in the EU CosIng database. sr-(sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40) is a single chain recombinant peptide, produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the gene from sh-Polypeptide-158, Tripeptide-46, and Hexapeptide-40. The fusion peptide contains 100 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.
Is Sr-(Sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40) allowed in cosmetics in the EU?
Yes. Sr-(Sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40) is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Sr-(Sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40) do in cosmetic products?
Sr-(Sh-Polypeptide-158 Tripeptide-46 Hexapeptide-40) is declared in the EU cosmetic ingredient inventory with these functions: hair conditioning, skin protecting, skin conditioning - miscellaneous.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 30/04/2025