Tetrapeptide-155
A cosmetic ingredient used as chelating, hair waving or straightening, eyelash conditioning in skincare, haircare, and personal-care products sold in the European Union.
What is it?
Tetrapeptide-155 is the synthetic peptide consisting of glycine, histidine, leucine and proline.
What does it do?
Tetrapeptide-155 is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Chelating
binds metal ions to prevent them from interfering with formulation stability
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Hair waving or straightening
permanently changes the shape of hair through chemical reduction and re-oxidation of the hair's disulfide bonds
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Eyelash conditioning
improves the appearance, feel, or condition of eyelashes
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Skin conditioning - miscellaneous
improves skin condition through mechanisms not classified under the more specific emollient or humectant subcategories
EU regulatory status
Tetrapeptide-155 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Tetrapeptide-155?
Tetrapeptide-155 is a cosmetic ingredient catalogued in the EU CosIng database. Tetrapeptide-155 is the synthetic peptide consisting of glycine, histidine, leucine and proline.
Is Tetrapeptide-155 allowed in cosmetics in the EU?
Yes. Tetrapeptide-155 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Tetrapeptide-155 do in cosmetic products?
Tetrapeptide-155 is declared in the EU cosmetic ingredient inventory with these functions: chelating, hair waving or straightening, eyelash conditioning, skin conditioning - miscellaneous.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 19/05/2026