Tri Sr-(Dipeptide-88 Penta Hydroxylated Octa Sh-Polypeptide-69)
A cosmetic ingredient used as astringent, bulking, film forming in skincare, haircare, and personal-care products sold in the European Union.
What is it?
Tri sr-(Dipeptide-88 Penta Hydroxylated Octa sh-Polypeptide-69) is a trimer of the single chain recombinant peptide produced by fermentation in Pichia pastoris. The starting gene is synthesized by the fusion of the genes from Dipeptide-88 and eight repeats of sh-Polypeptide-69 where the prolines have been hydroxylated to hydroxyproline. The fusion peptide contains 314 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence from the 20 standard amino acids.
What does it do?
Tri Sr-(Dipeptide-88 Penta Hydroxylated Octa Sh-Polypeptide-69) is listed in the EU cosmetic ingredient inventory with the following declared functions:
-
Astringent
tightens or contracts skin tissue and pores, often used in toners and after-shave products
-
Bulking
adds volume or mass to a product without significantly changing its other properties
-
Film forming
forms a thin continuous film on skin, hair, or nails — used in long-wear makeup, sunscreens, and hairsprays
-
Skin protecting
helps shield skin from external environmental factors
-
Skin conditioning - humectant
increases skin moisture by attracting water
EU regulatory status
Tri Sr-(Dipeptide-88 Penta Hydroxylated Octa Sh-Polypeptide-69) is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Tri Sr-(Dipeptide-88 Penta Hydroxylated Octa Sh-Polypeptide-69)?
Tri Sr-(Dipeptide-88 Penta Hydroxylated Octa Sh-Polypeptide-69) is a cosmetic ingredient catalogued in the EU CosIng database. Tri sr-(Dipeptide-88 Penta Hydroxylated Octa sh-Polypeptide-69) is a trimer of the single chain recombinant peptide produced by fermentation in Pichia pastoris. The starting gene is synthesized by the fusion of the genes from Dipeptide-88 and eight repeats of sh-Polypeptide-69 where the prolines have been hydroxylated to hydroxyproline. The fusion peptide contains 314 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence from the 20 standard amino acids.
Is Tri Sr-(Dipeptide-88 Penta Hydroxylated Octa Sh-Polypeptide-69) allowed in cosmetics in the EU?
Yes. Tri Sr-(Dipeptide-88 Penta Hydroxylated Octa Sh-Polypeptide-69) is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Tri Sr-(Dipeptide-88 Penta Hydroxylated Octa Sh-Polypeptide-69) do in cosmetic products?
Tri Sr-(Dipeptide-88 Penta Hydroxylated Octa Sh-Polypeptide-69) is declared in the EU cosmetic ingredient inventory with these functions: astringent, bulking, film forming, skin protecting, skin conditioning - humectant.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 07/05/2026