Uv-Irradiated Human Immortal Keratinocyte Conditioned Media
A cosmetic ingredient used as skin conditioning - emollient, hair conditioning, skin conditioning - humectant in skincare, haircare, and personal-care products sold in the European Union.
What is it?
UV-Irradiated Human Immortal Keratinocyte Conditioned Media is the growth media removed from cultures of irradiated human keratinocytes after several days of growth. The cells are immortalized spontaneously and irradiated with UVB light. The starting media is a serum-free nutrient media.
What does it do?
Uv-Irradiated Human Immortal Keratinocyte Conditioned Media is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Skin conditioning - emollient
softens the skin by reducing roughness and friction between skin cells
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Hair conditioning
improves the appearance, feel, and manageability of hair
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Skin conditioning - humectant
increases skin moisture by attracting water
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Skin conditioning - miscellaneous
improves skin condition through mechanisms not classified under the more specific emollient or humectant subcategories
EU regulatory status
This ingredient is banned in the European Union.
Uv-Irradiated Human Immortal Keratinocyte Conditioned Media is listed under Annex II of EU Cosmetics Regulation 1223/2009 (entry 416), making it prohibited in cosmetic products placed on the EU market.
Frequently asked questions
What is Uv-Irradiated Human Immortal Keratinocyte Conditioned Media?
Uv-Irradiated Human Immortal Keratinocyte Conditioned Media is a cosmetic ingredient catalogued in the EU CosIng database. UV-Irradiated Human Immortal Keratinocyte Conditioned Media is the growth media removed from cultures of irradiated human keratinocytes after several days of growth. The cells are immortalized spontaneously and irradiated with UVB light. The starting media is a serum-free nutrient media.
Is Uv-Irradiated Human Immortal Keratinocyte Conditioned Media allowed in cosmetics in the EU?
No. Uv-Irradiated Human Immortal Keratinocyte Conditioned Media is banned for use in cosmetic products in the EU under Annex II of Regulation 1223/2009.
What does Uv-Irradiated Human Immortal Keratinocyte Conditioned Media do in cosmetic products?
Uv-Irradiated Human Immortal Keratinocyte Conditioned Media is declared in the EU cosmetic ingredient inventory with these functions: skin conditioning - emollient, hair conditioning, skin conditioning - humectant, skin conditioning - miscellaneous.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 25/06/2026