Stearyldisulfidehexyl Sh-Dna-2 Peg-45/sh-Rna-1
A cosmetic ingredient used as hair conditioning in skincare, haircare, and personal-care products sold in the European Union.
What is it?
Stearyldisulfidehexyl sh-DNA-2 PEG-45/sh-RNA-1 is a synthetic human RNA strand conjugated with a synthetic human complementary DNA strand modified at the 5' end with Stearyldisulfidehexyl and at the 3' end with polyethylene glycol. The RNA is an androgen-receptor-specific siRNA comprised of 19 ribonucleotides. The modified DNA is a complementary strand comprised of 19 deoxyribonucleotides selected from the isoform-common region of human androgen receptor mRNAs isoform 1. This was developed for effective and specific degradation of mRNA coding androgen receptor.
What does it do?
Stearyldisulfidehexyl Sh-Dna-2 Peg-45/sh-Rna-1 is listed in the EU cosmetic ingredient inventory with the following declared functions:
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Hair conditioning
improves the appearance, feel, and manageability of hair
EU regulatory status
Stearyldisulfidehexyl Sh-Dna-2 Peg-45/sh-Rna-1 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.
Frequently asked questions
What is Stearyldisulfidehexyl Sh-Dna-2 Peg-45/sh-Rna-1?
Stearyldisulfidehexyl Sh-Dna-2 Peg-45/sh-Rna-1 is a cosmetic ingredient catalogued in the EU CosIng database. Stearyldisulfidehexyl sh-DNA-2 PEG-45/sh-RNA-1 is a synthetic human RNA strand conjugated with a synthetic human complementary DNA strand modified at the 5' end with Stearyldisulfidehexyl and at the 3' end with polyethylene glycol. The RNA is an androgen-receptor-specific siRNA comprised of 19 ribonucleotides. The modified DNA is a complementary strand comprised of 19 deoxyribonucleotides selected from the isoform-common region of human androgen receptor mRNAs isoform 1. This was developed for effective and specific degradation of mRNA coding androgen receptor.
Is Stearyldisulfidehexyl Sh-Dna-2 Peg-45/sh-Rna-1 allowed in cosmetics in the EU?
Yes. Stearyldisulfidehexyl Sh-Dna-2 Peg-45/sh-Rna-1 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.
What does Stearyldisulfidehexyl Sh-Dna-2 Peg-45/sh-Rna-1 do in cosmetic products?
Stearyldisulfidehexyl Sh-Dna-2 Peg-45/sh-Rna-1 is declared in the EU cosmetic ingredient inventory with these functions: hair conditioning.
Related ingredients
Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 28/10/2019