Allowed in EU

Stearyldisulfidehexyl Sh-Dna-3 Peg-45/sh-Rna-2

Q: What is Stearyldisulfidehexyl Sh-Dna-3 Peg-45/Sh-Rna-2?

Stearyldisulfidehexyl Sh-Dna-3 Peg-45/Sh-Rna-2 is a cosmetic ingredient catalogued in the EU CosIng database. Stearyldisulfidehexyl sh-DNA-3 PEG-45/sh-RNA-2 is a synthetic human RNA strand conjugated with a synthetic human complementary DNA strand which is modified at the 5' end with Stearyldisulfidehexyl and at the 3' end with polyethylene glycol. The RNA is a Dickkopf-1-specific siRNA comprised of 19 ribonucleotides. The modified DNA is a complementary strand comprised of 19 deoxyribonucleotides selected from the human Dickkopf-1 mRNAs. This was developed for effective and specific degradation of mRNA coding for Dickkopf-1.

Q: Is Stearyldisulfidehexyl Sh-Dna-3 Peg-45/Sh-Rna-2 allowed in cosmetics in the EU?

Yes. Stearyldisulfidehexyl Sh-Dna-3 Peg-45/Sh-Rna-2 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.

Q: What does Stearyldisulfidehexyl Sh-Dna-3 Peg-45/Sh-Rna-2 do in cosmetic products?

Stearyldisulfidehexyl Sh-Dna-3 Peg-45/Sh-Rna-2 is declared in the EU cosmetic ingredient inventory with these functions: hair conditioning.

A cosmetic ingredient used as hair conditioning in skincare, haircare, and personal-care products sold in the European Union.

What is it?

Stearyldisulfidehexyl sh-DNA-3 PEG-45/sh-RNA-2 is a synthetic human RNA strand conjugated with a synthetic human complementary DNA strand which is modified at the 5' end with Stearyldisulfidehexyl and at the 3' end with polyethylene glycol. The RNA is a Dickkopf-1-specific siRNA comprised of 19 ribonucleotides. The modified DNA is a complementary strand comprised of 19 deoxyribonucleotides selected from the human Dickkopf-1 mRNAs. This was developed for effective and specific degradation of mRNA coding for Dickkopf-1.

What does it do?

Stearyldisulfidehexyl Sh-Dna-3 Peg-45/sh-Rna-2 is listed in the EU cosmetic ingredient inventory with the following declared functions:

Hair conditioning
improves the appearance, feel, and manageability of hair

EU regulatory status

Stearyldisulfidehexyl Sh-Dna-3 Peg-45/sh-Rna-2 is allowed for use in cosmetic products in the European Union under Regulation 1223/2009. It is not subject to a specific Annex restriction at the time of writing.

Frequently asked questions

What is Stearyldisulfidehexyl Sh-Dna-3 Peg-45/sh-Rna-2?

Stearyldisulfidehexyl Sh-Dna-3 Peg-45/sh-Rna-2 is a cosmetic ingredient catalogued in the EU CosIng database. Stearyldisulfidehexyl sh-DNA-3 PEG-45/sh-RNA-2 is a synthetic human RNA strand conjugated with a synthetic human complementary DNA strand which is modified at the 5' end with Stearyldisulfidehexyl and at the 3' end with polyethylene glycol. The RNA is a Dickkopf-1-specific siRNA comprised of 19 ribonucleotides. The modified DNA is a complementary strand comprised of 19 deoxyribonucleotides selected from the human Dickkopf-1 mRNAs. This was developed for effective and specific degradation of mRNA coding for Dickkopf-1.

Is Stearyldisulfidehexyl Sh-Dna-3 Peg-45/sh-Rna-2 allowed in cosmetics in the EU?

Yes. Stearyldisulfidehexyl Sh-Dna-3 Peg-45/sh-Rna-2 is allowed for use in cosmetic products in the EU under Regulation 1223/2009.

What does Stearyldisulfidehexyl Sh-Dna-3 Peg-45/sh-Rna-2 do in cosmetic products?

Stearyldisulfidehexyl Sh-Dna-3 Peg-45/sh-Rna-2 is declared in the EU cosmetic ingredient inventory with these functions: hair conditioning.

Related ingredients

Source: EU CosIng database (European Commission). This page is derived from public-sector information published by the European Commission. · Last updated: 28/10/2019